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When Can Biosimilars Be Automatically Substituted? U.S. Rules Explained
18 Jan, 2026

When Can Biosimilars Be Automatically Substituted? U.S. Rules Explained

by Trevor Ockley | Jan, 18 2026 | Health | 10 Comments

In the U.S., only certain biosimilars are designated as interchangeable by the FDA, allowing pharmacists to swap them for brand-name biologics without a doctor’s approval. Learn how it works, which ones qualify, and why state laws make it complicated.

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